At ORY®, we believe you should know what’s in your products and why. This page lists the published research behind what we say about Chamomile + Calendula Infused Squalane / Caprylic-Capric Triglyceride. Each section starts with our claim, then tells you how well the research supports it, then lists the sources so you can read them yourself.
Please note: Some studies on this page tested chamomile and calendula for medical conditions, and most used extracts, creams, or oral forms rather than an oil infusion. We share them for transparency. ORY® infused oils are cosmetics and are not intended to treat any condition.
How to read this page Supported — backed by peer-reviewed research or official safety reviews. Supported, with caveats — the research points this way, but mostly from laboratory or animal studies, or at different strengths than ORY® uses. Limited evidence — little or no published research yet. We say so openly. |
1. General Description and Role
Claim: Chamomile + Calendula Infused Squalane / Caprylic-Capric Triglyceride is an ORY® Build-Your-Own infused oil: dried chamomile and calendula steeped in the customer’s choice of Squalane or Caprylic/Capric Triglyceride, then strained and protected with vitamin E and rosemary extract. It helps skin and hair feel soft, nourished, and comfortable. |
Verification: Supported. The Cosmetic Ingredient Review (CIR) Expert Panel has found each component safe in cosmetics: German chamomile ingredients are safe when formulated to be non-sensitizing; calendula-derived ingredients are safe as used; squalane is safe as used; caprylic/capric triglyceride is safe as used. CIR has not reviewed this specific blend.
Citations:
- Johnson, W., Boyer, I., Bergfeld, W. F., et al. (2018). Amended safety assessment of Chamomilla recutita-derived ingredients as used in cosmetics. International Journal of Toxicology, 37(3 Suppl), 51S–79S. https://doi.org/10.1177/1091581818801814
- What it shows: CIR safety assessment (Chamomile).
- Andersen, F. A., Bergfeld, W. F., Belsito, D. V., et al. (2010). Final report of the Cosmetic Ingredient Review Expert Panel amended safety assessment of Calendula officinalis-derived cosmetic ingredients. International Journal of Toxicology, 29(6 Suppl), 221S–243S. https://doi.org/10.1177/1091581810384883
- What it shows: CIR safety assessment (Calendula).
- Elder, R. L. (Ed.). (1982). Final report on the safety assessment of squalane and squalene. Journal of the American College of Toxicology, 1(2), 37–56 (reaffirmed by CIR in 2003 and 2023). https://doi.org/10.1177/10915818231204276
- What it shows: CIR safety assessment (Squalane).
- Cosmetic Ingredient Review Expert Panel. (2022). Amended safety assessment of triglycerides as used in cosmetics. International Journal of Toxicology. https://doi.org/10.1177/10915818221123790
- What it shows: CIR safety assessment (Caprylic/Capric Triglyceride).
- Johnson, W., Boyer, I., Bergfeld, W. F., et al. (2018). Amended safety assessment of Chamomilla recutita-derived ingredients as used in cosmetics. International Journal of Toxicology, 37(3 Suppl), 51S–79S. https://doi.org/10.1177/1091581818801814
2. Composition and Production
Claim: German chamomile flowers contribute alpha-bisabolol, bisabolol oxides, matricin, and some apigenin. Calendula petals contribute oil-soluble faradiol esters and carotenoids. The carrier makes up most of the product. Squalane is weightless and non-greasy and suits all skin types. Caprylic/Capric Triglyceride is light, odorless, and stable and suits all skin types. |
Verification: Supported. ORY® steeps dried (never fresh) botanicals in the carrier, strains them out, and adds 0.5–1% vitamin E and 0.1% rosemary extract. An oil infusion captures mainly oil-soluble compounds, so its strength differs from the extracts used in research. ORY® infused oils are made by steeping dried plant material in a carrier oil. The carrier oil makes up most of the finished product, so its own properties matter as much as the botanical’s — including allergy: nut-derived carrier oils such as sweet almond oil may not suit people with tree-nut allergies.
Citations:
- Johnson, W., Boyer, I., Bergfeld, W. F., et al. (2018). Amended safety assessment of Chamomilla recutita-derived ingredients as used in cosmetics. International Journal of Toxicology, 37(3 Suppl), 51S–79S. https://doi.org/10.1177/1091581818801814
- What it shows: Describes botanical composition.
- Andersen, F. A., Bergfeld, W. F., Belsito, D. V., et al. (2010). Final report of the Cosmetic Ingredient Review Expert Panel amended safety assessment of Calendula officinalis-derived cosmetic ingredients. International Journal of Toxicology, 29(6 Suppl), 221S–243S. https://doi.org/10.1177/1091581810384883
- What it shows: Describes botanical composition.
- Elder, R. L. (Ed.). (1982). Final report on the safety assessment of squalane and squalene. Journal of the American College of Toxicology, 1(2), 37–56 (reaffirmed by CIR in 2003 and 2023). https://doi.org/10.1177/10915818231204276
- What it shows: Describes carrier composition.
- Cosmetic Ingredient Review Expert Panel. (2022). Amended safety assessment of triglycerides as used in cosmetics. International Journal of Toxicology. https://doi.org/10.1177/10915818221123790
- What it shows: Describes carrier composition.
- Johnson, W., Boyer, I., Bergfeld, W. F., et al. (2018). Amended safety assessment of Chamomilla recutita-derived ingredients as used in cosmetics. International Journal of Toxicology, 37(3 Suppl), 51S–79S. https://doi.org/10.1177/1091581818801814
3. Skin Type Suitability
Claim: This infused oil suits all skin types, including dry, sensitive, and oily skin, because both carriers are light and non-greasy. People with daisy-family allergy should patch test or avoid it. |
Verification: Supported, with caveats. We found no clinical studies of this blend. Suitability is based on the carrier and the safety data for each ingredient. Chamomile and calendula can cause allergy in people sensitive to daisy-family plants.
Citations:
- Paulsen, E. (2002). Contact sensitization from Compositae-containing herbal remedies and cosmetics. Contact Dermatitis, 47(4), 189–198. https://doi.org/10.1034/j.1600-0536.2002.470401.x
- What it shows: Review of daisy-family allergy.
- Elder, R. L. (Ed.). (1982). Final report on the safety assessment of squalane and squalene. Journal of the American College of Toxicology, 1(2), 37–56 (reaffirmed by CIR in 2003 and 2023). https://doi.org/10.1177/10915818231204276
- What it shows: Carrier safety data.
- Cosmetic Ingredient Review Expert Panel. (2022). Amended safety assessment of triglycerides as used in cosmetics. International Journal of Toxicology. https://doi.org/10.1177/10915818221123790
- What it shows: Carrier safety data.
- Paulsen, E. (2002). Contact sensitization from Compositae-containing herbal remedies and cosmetics. Contact Dermatitis, 47(4), 189–198. https://doi.org/10.1034/j.1600-0536.2002.470401.x
4. Hair and Scalp Suitability
Claim: In haircare, this infused oil helps hair feel soft and look glossy. |
Verification: Limited evidence. Hair-growth and hair-loss claims are drug claims, and ORY® does not make them. ORY® haircare products are not intended to treat dandruff or scalp conditions.
Citations:
- U.S. Food and Drug Administration. 21 CFR 310.527 — Drug products offered over-the-counter for external use as hair growers or for hair loss prevention. https://www.law.cornell.edu/cfr/text/21/310.527
- What it shows: FDA treats hair-growth and hair-loss products as drugs.
- U.S. Food and Drug Administration. 21 CFR 310.527 — Drug products offered over-the-counter for external use as hair growers or for hair loss prevention. https://www.law.cornell.edu/cfr/text/21/310.527
5. Benefits
Claim: This infused oil helps skin and hair feel soft, smooth, and nourished and provides antioxidant support. |
Verification: Supported, with caveats. Most of the moisturizing benefit comes from the carrier. Reviews describe chamomile’s anti-inflammatory activity, mostly from lab and animal studies; a chamomile cream was studied in eczema, a medical use. Calendula has been studied for wounds and for skin reactions during radiation therapy, with mixed trial results; these are medical uses. ORY® does not make wound, eczema, acne, sun-protection, or hair-growth claims for this oil.
Citations:
- Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with a bright future. Molecular Medicine Reports, 3(6), 895–901. https://pubmed.ncbi.nlm.nih.gov/21132119/
- What it shows: Review of chamomile.
- Patzelt-Wenczler, R., & Ponce-Pöschl, E. (2000). Proof of efficacy of Kamillosan® cream in atopic eczema. European Journal of Medical Research, 5(4), 171–175. https://pubmed.ncbi.nlm.nih.gov/10799352/
- What it shows: Eczema study (a medical use).
- Givol, O., Kornhaber, R., Visentin, D., Cleary, M., Haik, J., & Harats, M. (2019). A systematic review of Calendula officinalis extract for wound healing. Wound Repair and Regeneration, 27(5), 548–561. https://doi.org/10.1111/wrr.12737
- What it shows: Systematic review of wound healing (a medical use).
- Pommier, P., Gomez, F., Sunyach, M. P., D’Hombres, A., Carrie, C., & Montbarbon, X. (2004). Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer. Journal of Clinical Oncology, 22(8), 1447–1453. https://doi.org/10.1200/JCO.2004.07.063
- What it shows: Radiation dermatitis trial (a medical use).
- Sharp, L., Finnilä, K., Johansson, H., Abrahamsson, M., Hatschek, T., & Bergenmar, M. (2013). No differences between Calendula cream and aqueous cream in the prevention of acute radiation skin reactions – Results from a randomised blinded trial. European Journal of Oncology Nursing, 17(4), 429–435. https://doi.org/10.1016/j.ejon.2012.11.003
- What it shows: Later trial with no difference from a plain cream.
- Huang, Z. R., Lin, Y. K., & Fang, J. Y. (2009). Biological and pharmacological activities of squalene and related compounds: Potential uses in cosmetic dermatology. Molecules, 14(1), 540–554. https://www.mdpi.com/1420-3049/14/1/540
- What it shows: Review of squalane.
- Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with a bright future. Molecular Medicine Reports, 3(6), 895–901. https://pubmed.ncbi.nlm.nih.gov/21132119/
6. Use Across ORY® Product Lines
Claim: Chamomile + Calendula Infused Squalane / Caprylic-Capric Triglyceride is used in all four ORY® product lines; its soap role depends on the carrier. |
Verification: Supported. Soap use by carrier: Squalane — does not saponify; superfat only (1–3%); Caprylic/Capric Triglyceride — small superfat only (2–5%). Being oil-only, the infusion needs no preservative if kept free of water.
| Product line | Typical level | How ORY® uses it |
| Skincare | 5–100% | Calming facial oils, balms, eye-area oils (squalane), and cleansing oils (CCT). |
| Haircare | 5–100% | Scalp oils and light ends serums. |
| Handmade Soap | 1–5% superfat | Superfat at trace only. |
| Cosmetics | 5–30% | Lip oils, foundation emollient, cream blush, and makeup removers. |
Citations:
- Elder, R. L. (Ed.). (1982). Final report on the safety assessment of squalane and squalene. Journal of the American College of Toxicology, 1(2), 37–56 (reaffirmed by CIR in 2003 and 2023). https://doi.org/10.1177/10915818231204276
- What it shows: CIR safety assessment (Squalane).
- Cosmetic Ingredient Review Expert Panel. (2022). Amended safety assessment of triglycerides as used in cosmetics. International Journal of Toxicology. https://doi.org/10.1177/10915818221123790
- What it shows: CIR safety assessment (Caprylic/Capric Triglyceride).
- U.S. Food and Drug Administration. Is It a Cosmetic, a Drug, or Both? (Or Is It Soap?) https://www.fda.gov/cosmetics/cosmetics-laws-regulations/it-cosmetic-drug-or-both-or-it-soap
- What it shows: FDA explains how soap is regulated.
- Elder, R. L. (Ed.). (1982). Final report on the safety assessment of squalane and squalene. Journal of the American College of Toxicology, 1(2), 37–56 (reaffirmed by CIR in 2003 and 2023). https://doi.org/10.1177/10915818231204276
7. Pros
Claim: CIR-reviewed botanicals in a carrier matched to each customer’s skin and hair. |
Verification: Supported. Each component has a CIR safety conclusion.
Citations:
- Johnson, W., Boyer, I., Bergfeld, W. F., et al. (2018). Amended safety assessment of Chamomilla recutita-derived ingredients as used in cosmetics. International Journal of Toxicology, 37(3 Suppl), 51S–79S. https://doi.org/10.1177/1091581818801814
- What it shows: CIR safety assessment (Chamomile).
- Andersen, F. A., Bergfeld, W. F., Belsito, D. V., et al. (2010). Final report of the Cosmetic Ingredient Review Expert Panel amended safety assessment of Calendula officinalis-derived cosmetic ingredients. International Journal of Toxicology, 29(6 Suppl), 221S–243S. https://doi.org/10.1177/1091581810384883
- What it shows: CIR safety assessment (Calendula).
- Elder, R. L. (Ed.). (1982). Final report on the safety assessment of squalane and squalene. Journal of the American College of Toxicology, 1(2), 37–56 (reaffirmed by CIR in 2003 and 2023). https://doi.org/10.1177/10915818231204276
- What it shows: CIR safety assessment (Squalane).
- Cosmetic Ingredient Review Expert Panel. (2022). Amended safety assessment of triglycerides as used in cosmetics. International Journal of Toxicology. https://doi.org/10.1177/10915818221123790
- What it shows: CIR safety assessment (Caprylic/Capric Triglyceride).
- Johnson, W., Boyer, I., Bergfeld, W. F., et al. (2018). Amended safety assessment of Chamomilla recutita-derived ingredients as used in cosmetics. International Journal of Toxicology, 37(3 Suppl), 51S–79S. https://doi.org/10.1177/1091581818801814
8. Cons
Claim: Infusion strength varies, the botanical research used other forms, and some ingredients carry allergy cautions. |
Verification: Supported. We list these limits so you have the full picture:
- Variable strength. Depends on botanical quality, ratio, and steeping time.
- Different forms in research. Studies used extracts, creams, essential oils, or oral products, not this infusion.
- Daisy-family allergy. Chamomile and calendula can cause allergy.
- No blend-specific trials. Evidence is for individual ingredients.
Citations:
- Paulsen, E. (2002). Contact sensitization from Compositae-containing herbal remedies and cosmetics. Contact Dermatitis, 47(4), 189–198. https://doi.org/10.1034/j.1600-0536.2002.470401.x
- What it shows: Allergy.
- Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with a bright future. Molecular Medicine Reports, 3(6), 895–901. https://pubmed.ncbi.nlm.nih.gov/21132119/
- What it shows: Review of chamomile.
- Patzelt-Wenczler, R., & Ponce-Pöschl, E. (2000). Proof of efficacy of Kamillosan® cream in atopic eczema. European Journal of Medical Research, 5(4), 171–175. https://pubmed.ncbi.nlm.nih.gov/10799352/
- What it shows: Eczema study (a medical use).
- Paulsen, E. (2002). Contact sensitization from Compositae-containing herbal remedies and cosmetics. Contact Dermatitis, 47(4), 189–198. https://doi.org/10.1034/j.1600-0536.2002.470401.x
9. Safety Notes
Claim: Patch test before use; for external use only. |
Verification: Supported. Follow these precautions:
- Patch test any new product on a small area for 24–48 hours before full use.
- If you are allergic to ragweed, chamomile, daisies, or other plants in the daisy (Asteraceae) family, patch test carefully or avoid this product.
- If you have a nut or seed allergy, check the carrier before use.
- Store away from heat and light, keep water out of the bottle, and discard if it smells rancid.
- Stop use if redness, burning, itching, or rash occurs, and talk to a healthcare provider.
- For external use only. Avoid the eyes.
- If you are pregnant, nursing, have a medical condition, or are buying for a child, ask a healthcare provider before use.
Citations:
- Paulsen, E. (2002). Contact sensitization from Compositae-containing herbal remedies and cosmetics. Contact Dermatitis, 47(4), 189–198. https://doi.org/10.1034/j.1600-0536.2002.470401.x
- What it shows: Allergy.
- Elder, R. L. (Ed.). (1982). Final report on the safety assessment of squalane and squalene. Journal of the American College of Toxicology, 1(2), 37–56 (reaffirmed by CIR in 2003 and 2023). https://doi.org/10.1177/10915818231204276
- What it shows: Carrier safety.
- Cosmetic Ingredient Review Expert Panel. (2022). Amended safety assessment of triglycerides as used in cosmetics. International Journal of Toxicology. https://doi.org/10.1177/10915818221123790
- What it shows: Carrier safety.
- Paulsen, E. (2002). Contact sensitization from Compositae-containing herbal remedies and cosmetics. Contact Dermatitis, 47(4), 189–198. https://doi.org/10.1034/j.1600-0536.2002.470401.x
10. Product-line notes
- ORY® Skincare: For external use only. Not for deep or puncture wounds, animal bites, or serious burns.
- ORY® Haircare: Designed for scalp comfort and the look and feel of hair. Not intended to treat dandruff or scalp conditions, or to promote hair growth or prevent hair loss. If you notice sudden shedding or a persistent itchy, flaking scalp, see a dermatologist.
- ORY® Handmade Soap: Handmade soap is naturally alkaline, and each bar may vary slightly in color, scent, and texture. Not intended to treat eczema or any skin condition.
- ORY® Cosmetics: Lip products are not intended to treat or protect chapped or cracked lips. Do not share applicators, and replace any product that changes color, smell, or texture.
11. References
Peer-reviewed research
- Andersen, F. A., Bergfeld, W. F., Belsito, D. V., et al. (2010). Final report of the Cosmetic Ingredient Review Expert Panel amended safety assessment of Calendula officinalis-derived cosmetic ingredients. International Journal of Toxicology, 29(6 Suppl), 221S–243S. https://doi.org/10.1177/1091581810384883
- Cosmetic Ingredient Review Expert Panel. (2022). Amended safety assessment of triglycerides as used in cosmetics. International Journal of Toxicology. https://doi.org/10.1177/10915818221123790
- Elder, R. L. (Ed.). (1982). Final report on the safety assessment of squalane and squalene. Journal of the American College of Toxicology, 1(2), 37–56 (reaffirmed by CIR in 2003 and 2023). https://doi.org/10.1177/10915818231204276
- Givol, O., Kornhaber, R., Visentin, D., Cleary, M., Haik, J., & Harats, M. (2019). A systematic review of Calendula officinalis extract for wound healing. Wound Repair and Regeneration, 27(5), 548–561. https://doi.org/10.1111/wrr.12737
- Huang, Z. R., Lin, Y. K., & Fang, J. Y. (2009). Biological and pharmacological activities of squalene and related compounds: Potential uses in cosmetic dermatology. Molecules, 14(1), 540–554. https://www.mdpi.com/1420-3049/14/1/540
- Johnson, W., Boyer, I., Bergfeld, W. F., et al. (2018). Amended safety assessment of Chamomilla recutita-derived ingredients as used in cosmetics. International Journal of Toxicology, 37(3 Suppl), 51S–79S. https://doi.org/10.1177/1091581818801814
- Patzelt-Wenczler, R., & Ponce-Pöschl, E. (2000). Proof of efficacy of Kamillosan® cream in atopic eczema. European Journal of Medical Research, 5(4), 171–175. https://pubmed.ncbi.nlm.nih.gov/10799352/
- Paulsen, E. (2002). Contact sensitization from Compositae-containing herbal remedies and cosmetics. Contact Dermatitis, 47(4), 189–198. https://doi.org/10.1034/j.1600-0536.2002.470401.x
- Pommier, P., Gomez, F., Sunyach, M. P., D’Hombres, A., Carrie, C., & Montbarbon, X. (2004). Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer. Journal of Clinical Oncology, 22(8), 1447–1453. https://doi.org/10.1200/JCO.2004.07.063
- Sharp, L., Finnilä, K., Johansson, H., Abrahamsson, M., Hatschek, T., & Bergenmar, M. (2013). No differences between Calendula cream and aqueous cream in the prevention of acute radiation skin reactions – Results from a randomised blinded trial. European Journal of Oncology Nursing, 17(4), 429–435. https://doi.org/10.1016/j.ejon.2012.11.003
- Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with a bright future. Molecular Medicine Reports, 3(6), 895–901. https://pubmed.ncbi.nlm.nih.gov/21132119/
Government and regulatory sources
- U.S. Food and Drug Administration. 21 CFR 310.527 — Drug products offered over-the-counter for external use as hair growers or for hair loss prevention. https://www.law.cornell.edu/cfr/text/21/310.527
- U.S. Food and Drug Administration. Is It a Cosmetic, a Drug, or Both? (Or Is It Soap?) https://www.fda.gov/cosmetics/cosmetics-laws-regulations/it-cosmetic-drug-or-both-or-it-soap
